Updated: November 2025
The complete guide to OptiMSM™, how it supports hair, skin, and nails, and why it's the perfect complement to Functional Keratin™
OptiMSM™ is a highly pure and bioavailable form of methylsulfonylmethane (MSM), a naturally occurring sulphur compound found in plants, animals, and humans.
It's a patented form of MSM that undergoes rigorous manufacturing to ensure quality and efficacy.
But here's what makes it truly special: OptiMSM™ isn't just another supplement.
It's a critical nutrient that works synergistically with Functional Keratin™ to create comprehensive support for hair, skin, and nails.
In this blog, we'll explore the origins of OptiMSM™, its science-backed benefits, how it works with keratin, and why Kiri10 includes it in our premium formulations.
The Origins of OptiMSM™: A Discovery Story
The Discovery of MSM
The story of OptiMSM™ begins with methylsulfonylmethane (MSM) itself, a naturally occurring organic sulphur compound.
MSM exists in various plants, animals, and even in our own bodies.
But it wasn't until the 20th century that researchers recognised its potential for human health.
The Breakthrough Research
In the early 1980s, a team of researchers led by Dr. Stanley W. Jacob at the Oregon Health Sciences University began studying MSM's effects on human health.
Dr. Jacob and his team discovered:
MSM played a crucial role in supporting joint health
It effectively reduced inflammation
It improved overall wellbeing and resilience
These findings were groundbreaking.
The Development of OptiMSM™
To further explore MSM's potential, Dr. Jacob collaborated with renowned chemist Robert J. Herschler.
Together, they developed a unique, patented manufacturing process.
This process ensured the production of the purest and most bioavailable form of MSM available.
This marked the birth of OptiMSM™.
The OptiMSM™ Manufacturing Process
The precision behind the product:
Begins with high-quality raw materials sourced carefully
Involves multi-stage processing including distillation, purification, and filtration
Meticulously removes impurities and contaminants
Results in highly pure, bioactive MSM
Quality assurance:
Manufactured in the United States at state-of-the-art facilities
Adheres to strict quality control measures
ISO 9001:2015 certified for consistent quality and safety
This commitment to excellence has made OptiMSM™ trusted globally.
What Is OptiMSM™ Actually?
The Science
OptiMSM™ is a bioavailable form of MSM, an organic sulphur compound.
Sulphur is a critical mineral element in your body.
Why sulphur matters:
It's essential for collagen and keratin production
It supports the formation of connective tissue
It's necessary for healthy joint function
It plays a role in detoxification processes
Most people consume insufficient sulphur in modern diets.
Bioavailability
What makes OptiMSM™ superior is its bioavailability.
High bioavailability means:
Your body can absorb and utilise it efficiently
More of what you take actually reaches your cells
You need less to achieve results
Effects appear more quickly
Seven Major Benefits of OptiMSM™
Benefit 1: Joint Health Support
One of the most researched benefits of OptiMSM™ is joint health support.
How it works:
Provides sulphur, vital for cartilage and connective tissue
Supports the structural integrity of joints
May reduce joint discomfort and stiffness
Promotes mobility and flexibility
Who benefits:
Athletes and active people
People with joint concerns
Anyone interested in proactive joint health
Benefit 2: Reduced Inflammation
OptiMSM™ possesses powerful anti-inflammatory properties.
The inflammation connection:
Chronic inflammation underlies many health concerns
OptiMSM™ helps reduce systemic inflammation
This creates a foundation for better overall health
Particularly beneficial when combined with other anti-inflammatory practices
Benefit 3: Skin Health and Beauty
OptiMSM™ is widely recognised for its benefits to skin.
How it supports skin:
Promotes collagen production
Maintains skin elasticity and firmness
Supports healthy skin barrier function
Reduces the appearance of fine lines and wrinkles
Improves skin tone and complexion
Benefit 4: Enhanced Antioxidant Activity
OptiMSM™ possesses significant antioxidant properties.
Why antioxidants matter:
Free radicals cause oxidative stress
Oxidative stress accelerates ageing
Antioxidants neutralise free radicals
OptiMSM™'s antioxidant action protects cellular health
Benefit 5: Hair and Nail Health
OptiMSM™ contributes significantly to hair and nail strength.
How it works:
Provides sulphur essential for keratin production
Supports the structural integrity of hair and nails
Promotes stronger, more resilient growth
Reduces brittleness and breakage
When combined with Functional Keratin™, results are exceptional.
Benefit 6: Exercise Recovery
OptiMSM™ has been studied for its benefits in athletic recovery.
Benefits for athletes:
Reduces exercise-induced muscle damage
Decreases muscle soreness (DOMS)
Supports faster recovery between workouts
May improve athletic performance over time
Benefit 7: Immune and Allergy Support
Some research suggests OptiMSM™ may have antiallergic properties.
Potential mechanisms:
Reduces inflammatory response in allergic reactions
May alleviate nasal congestion
Modulates immune response appropriately
Supports respiratory health
OptiMSM™ and Functional Keratin™: The Perfect Partnership
Understanding Each Component
Functional Keratin™:
The building block protein for hair, skin, and nails
Provides structural support
Achieves 91% bio-identity to human keratin
Directly repairs damaged keratin structures
OptiMSM™:
Provides sulphur essential for keratin and collagen production
Supports the body's ability to make new keratin
Reduces inflammation that damages keratin
Works at the foundational level
How They Work Together
Think of it like building and maintaining a house:
Functional Keratin™ = the bricks and mortar
It provides the actual structural components
It repairs existing damage
It directly strengthens hair, skin, and nails
OptiMSM™ = the foundation and maintenance crew
It provides the minerals needed for building materials
It reduces inflammation damaging the structure
It supports your body's natural repair processes
The Synergistic Effect
Using both together creates:
More efficient keratin production
Better structural support for hair and nails
Reduced inflammation protecting new growth
Faster, more visible results
This is why Kiri10 includes OptiMSM™ in our formulations.
Clinical Research on OptiMSM™
Joint and Inflammation Studies
OptiMSM™ has been extensively studied for its health benefits.
Key research findings:
Arthritis & Rheumatism (2006): Study on MSM and osteoarthritis of the knee showed significant pain reduction and improved function
Rheumatology International (2008): Research on rheumatoid arthritis demonstrated efficacy in reducing joint symptoms
Phytotherapy Research (2012): Systematic review confirmed benefits for both osteoarthritis and rheumatoid arthritis
Exercise and Recovery Studies
Journal of the American College of Nutrition (2007): MSM showed benefits for plantar fasciitis pain and function
Journal of Rheumatology (2010): Demonstrated efficacy in treating tendinitis
Journal of the International Society of Sports Nutrition (2012): Showed significant reduction in delayed-onset muscle soreness (DOMS)
These studies confirm what users experience: OptiMSM™ delivers real, measurable benefits.
How Kiri10 Uses OptiMSM™
Our Formulation Philosophy
At Kiri10, we don't just use individual ingredients.
We combine them strategically for maximum benefit.
OptiMSM™ is a core component of our keratin supplements.
Why we include it:
It enhances Functional Keratin™ effectiveness
It reduces inflammation protecting hair growth
It supports the body's natural keratin production
It provides comprehensive nutritional support
Our Complete System
Internal Support (Daily):
Functional Keratin™ supplements infused with OptiMSM™
Delivers both the building blocks and the minerals needed
Supports hair, skin, and nail health simultaneously
External Support:
Triple-Keratin Complex™ haircare with OptiMSM™ (where applicable)
Topical products containing keratin and supportive ingredients
Lifestyle Support:
Anti-inflammatory practices
Adequate nutrition
Consistent self-care
Together, this creates transformation.
Why OptiMSM™ Matters for Your Results
The Missing Link in Most Supplements
Most keratin supplements provide just keratin.
But keratin alone has limitations.
Your body needs the raw materials to build new keratin.
That's where OptiMSM™ comes in.
The Difference in Results
With keratin alone:
Temporary improvement
Limited structural repair
Body still lacks building materials for new keratin
With keratin plus OptiMSM™:
Lasting structural improvement
Body can produce new keratin efficiently
Inflammation reduced, supporting growth
Results compound over time
This is why Kiri10 is different.
References and Further Reading
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OptiMSM™ Origins and Manufacturing - OptiMSM Official - Official information on OptiMSM™ production
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MSM and Joint Health - Arthritis & Rheumatism (2006) - Clinical study on osteoarthritis
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Systemic Review of MSM Research - Phytotherapy Research (2012) - Comprehensive review of MSM benefits
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Effect of keraGEN IV Keratin Oral Supplementation - Lincoln Agritech - Clinical study on Functional Keratin™
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MSM and Exercise Recovery - Journal of International Society of Sports Nutrition (2012) - Research on DOMS reduction
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Sulphur and Collagen Production - PMC - Scientific overview of sulphur's role
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KiriGlow Keratin Supplement - Kiri10 - Functional Keratin™ plus OptiMSM™ supplement
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